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克念菌素系球孢放线菌(Actinomycesglobisporus)的变种所产生的七烯大环内酯类抗生素,与国外杀念珠菌素(candicidi-ns)类似。由于其抗真菌活性较强,治疗霉菌性的呼吸道、眼角膜、阴道等感染疾病均有较好的疗效,临床应用已有阴道片及其水溶性钠盐二种剂型。 近期来国外报导了用杀念珠菌素经口服治疗老年前列腺增生的临床试验,获得一定效果,我院于1976年开始在上海几个医院将克念菌素试用于治疗前列腺增生症,初步获得较好的疗效,逐步扩大临床试验,共选择病例59例,经随访(3—10个月)共57例,报导如下。
Actinomyces globosum Actinomyces gracilis Actinomyces globosus produced by the seven cetides macrolide antibiotics, similar to foreign candicidin (candicidi-ns). Because of its strong antifungal activity, the treatment of fungal respiratory tract, cornea, vaginal infections and other diseases have a good effect, the clinical application of vaginal tablets and its two forms of water-soluble sodium salt. Recently, foreign reports of oral administration of Candida albicans oral treatment of elderly patients with benign prostatic hyperplasia clinical trials, access to certain effects, our hospital began in 1976 in several hospitals in Shanghai will be probiotics in the treatment of benign prostatic hyperplasia, preliminary gain more Good effect, and gradually expand clinical trials, a total of 59 cases were selected, were followed up (3-10 months) a total of 57 cases reported as follows.