论文部分内容阅读
三核苷酸重复序列扩增是三核苷酸重复序列的拷贝数在世代传递中逐渐增加的一种基因动态突变,现已发现近20种疾病的发生与这一突变相关。深入研究这些问题对此类和重复序列相关遗传病分子机理的探讨有重要的生物学意义和医学价值。
Trinucleotide repeat amplification is a gene mutation in which the copy number of trinucleotide repeats increases gradually during the transmission of the gene. It has been found that the occurrence of nearly 20 diseases is related to this mutation. In-depth study of these issues on such and repeat the genetic mechanism of genetic disease has important biological significance and medical value.