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目的研究在治疗婴儿重症肺炎中采取无创持续气道正压通气(CPAP)的临床效果。方法56例婴儿重症肺炎患儿采用抽签法随机分为参照组与实验组,每组28例。参照组患儿采用常规治疗,实验组患儿采用无创CPAP治疗,分析对比两组患儿经不同治疗后临床效果。结果实验组患儿临床治疗总有效率为96.43%,显著高于参照组的75.00%,差异具有统计学意义(P<0.05)。实验组患儿呼吸困难消失时间(0.89±0.08)d、肺部啰音消失时间(5.24±0.65)d、动脉血氧分压(PaO_2)(98.65±3.25)mm Hg(1 mm Hg=0.133 kPa)、动脉血氧饱和度(SaO_2)(97.62±3.56)mm Hg均明显优于参照组的(2.21±0.09)d、(7.11±0.44)d、(79.64±4.21)mm Hg、(84.21±4.38)mm Hg,差异具有统计学意义(P<0.05)。结论将无创CPAP治疗应用在婴儿重症肺炎中具有显著疗效,可以有效改善患儿呼吸情况以及血气情况,具备广泛应用的价值。
Objective To study the clinical effect of noninvasive continuous positive airway pressure (CPAP) in the treatment of severe pneumonia in infants. Methods Fifty-six infants with severe pneumonia were randomly divided into control group and experimental group by random sampling, 28 cases in each group. The reference group of children with conventional treatment, experimental group of children with non-invasive CPAP treatment, analysis of two groups of children after treatment with different clinical effects. Results The total effective rate of clinical treatment in experimental group was 96.43%, which was significantly higher than that in reference group (75.00%), the difference was statistically significant (P <0.05). In the experimental group, the disappearance of dyspnea (0.89 ± 0.08) d, the disappearance of pulmonary rales (5.24 ± 0.65) days and the PaO_2 (98.65 ± 3.25) mm Hg (1 mm Hg = 0.133 kPa) ), Arterial oxygen saturation (SaO_2) (97.62 ± 3.56) mm Hg were significantly better than those in the reference group (2.21 ± 0.09) d, (7.11 ± 0.44) d, (79.64 ± 4.21) mm Hg, (84.21 ± 4.38 ) mm Hg, the difference was statistically significant (P <0.05). Conclusion The application of non-invasive CPAP in severe pneumonia in infants has a significant effect, which can effectively improve the respiratory status and blood gas in children with wide application value.