论文部分内容阅读
许多放射生物学者,根据放射敏感性的法则(Bergonie—Tribondeau’s Law),对癌细胞与正常细胞的敏感性差异进行了若干定量性的研究。1956年Puck Marcus人工细胞培养法成功之后,使这一研究有了飞速发展。其结论同预想相反,即癌细胞与正常细胞从本质上对放射线的敏感性是相同的。在癌的治疗上,放射生物学者不仅对癌细胞本身,也对细胞存在的条件,即敏感性修饰因子努力进行探索。因此,在寻求新药的同时,也在考虑这种生物学的可能性,并逐一进行实验,以提高癌症的治疗效果。
Many radiobiologists have conducted quantitative studies on the sensitivity differences between cancer cells and normal cells according to the law of radiosensitivity (Bergonie-Tribondeau’s Law). After the success of the Puck Marcus artificial cell culture method in 1956, this research made rapid progress. The conclusion is contrary to expectations that cancer cells and normal cells are essentially the same sensitive to radiation. In the treatment of cancer, radiobiologists have endeavored to explore not only the cancer cells themselves but also the conditions in which the cells exist, namely the sensitivity modifiers. Therefore, while seeking new drugs, we are also considering the possibility of this biology and conducting experiments one by one to improve the therapeutic effect of cancer.