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研究ｔ－ＲＡ对胃癌细胞的作用和探讨其作用机理．结果表明：１）ｔ－ＲＡ能够有效地抑制胃癌细胞的生长．２）ｔ－ＲＡ能够降低胃癌细胞在软琼脂中形成集落的能力．３）ｔ－ＲＡ能够降低胃癌细胞的粘附能力．４）ｔ－ＲＡ能够抑制胃癌细胞在裸鼠中形成肿瘤的能力．４）扫描电镜观察显示，经ｔ－ＲＡ处理后，胃癌细胞表面的微绒毛消失．以上结果表明，ｔ－ＲＡ对胃癌细胞的恶性表型有显著的抑制作用．ｔ－ＲＡ可能作为治疗胃癌的有效药物．
To study the effect of t-RA on gastric cancer cells and to explore its mechanism of action. The results showed that: 1) t-RA can effectively inhibit the growth of gastric cancer cells. 2) t-RA can reduce the ability of gastric cancer cells to form colonies in soft agar. 3) t-RA can reduce the adhesion of gastric cancer cells. 4) t-RA can inhibit the ability of gastric cancer cells to form tumors in nude mice. 4) Scanning electron microscopy showed that the microvilli disappeared on the surface of gastric cancer cells after t-RA treatment. The above results show that t-RA has a significant inhibitory effect on the malignant phenotype of gastric cancer cells. t-RA may be an effective drug for the treatment of gastric cancer.