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目的探讨绝经后妇女泌尿系感染反复发作患者小剂量雌激素预防治疗的临床疗效。方法选取本院2010年1月~2013年6月96例绝经后泌尿系反复感染患者,按照自愿原则分为研究组和对照组,对照组患者应用常规抗生素类药物治疗;研究组患者在对照组基础上予以小剂量雌激素治疗,分析比较两组治疗效果及不良反应。结果研究组治疗效果明显优于对照组,治疗所需时间低于对照组,患者恢复时间更快速,不良反应相较于对照组明显减少,且复发率降低,两组差异有统计学意义(P<0.05)。结论小剂量雌激素治疗绝经后泌尿系统反复感染症状效果明显,值得临床推广应用。
Objective To investigate the clinical efficacy of low-dose estrogen prophylaxis in patients with recurrent urinary tract infections in postmenopausal women. Methods Ninety-six patients with post-menopausal urinary tract recurrent infection from January 2010 to June 2013 in our hospital were divided into study group and control group according to the principle of voluntariness. Patients in the control group were treated with conventional antibiotics. In the study group, On the basis of small doses of estrogen therapy, analysis of the two groups of treatment and adverse reactions. Results The treatment group was significantly better than the control group, the treatment time was lower than the control group, the patients recovered faster, the adverse reaction was significantly reduced compared with the control group, and the recurrence rate decreased, the difference between the two groups was statistically significant (P <0.05). Conclusion Low dose estrogen treatment of postmenopausal symptoms of recurrent urinary tract infection is obvious, worthy of clinical application.