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我院22例原发性肝癌病人采用手术加放疗的综合治疗措施,全部病人均为男性,年龄15～69岁,平均44.5岁。病理诊断:肝细胞癌21例,胆管细胞癌1例。17例(77.3％)合并有肝硬变,19例(86.4％)的甲胎蛋白对流法为阳性。临床分期:Ⅰ期6例,Ⅱ期11例,Ⅲ期5例。手术种类包括:肝切除术17例(局部切除5例,右半肝切除5例,左外叶切除2例,左半肝切除2例,右三叶切除2例和左内叶切除1例),姑息性手术5例(肝动脉结扎或肝动脉栓塞4例,肝动脉插管化疗1例)。放射治疗用~(60)钴局部或全肝照射。 截至1983年5月止,本组得到随访的19例生存均已超过半年,其治后1、2、3、4年生存率分别为78.9％、66.7％、64.3％和44.4％。中位生存期为36月。 本组综合治疗显示使人鼓舞的效果,在目前它比肝切除、放疗或其他任阿综合治疗为优。
22 patients with primary liver cancer in our hospital were treated with surgery and radiotherapy. All patients were male, aged from 15 to 69 years old, with an average of 44.5 years old. Pathological diagnosis: 21 cases of hepatocellular carcinoma, 1 case of cholangiocarcinoma. Seventeen cases (77.3%) had liver cirrhosis and 19 cases (86.4%) had positive alpha fetoprotein convection. Clinical stage: 6 cases of stage I, 11 cases of stage II, and 5 cases of stage III. The types of surgery included: hepatectomy in 17 cases (5 in local resection, 5 in right hemihepatectomy, 2 in left lateral lobectomy, 2 in left hemihepatectomy, 2 in right tricusectomy, and 1 in left lobectomy) Palliative surgery in 5 cases (hepatic artery ligation or hepatic artery embolization in 4 cases, hepatic artery catheterization in 1 case). Radiation therapy uses ~(60) cobalt for local or whole liver irradiation. By the end of May 1983, the survival rate of the 19 cases that had been followed in this group had exceeded six months. The survival rates at 1, 2, 3, and 4 years after treatment were 78.9%, 66.7%, 64.3%, and 44.4%, respectively. The median survival period is 36 months. This group of comprehensive treatment shows encouraging results, at the moment it is superior to liver resection, radiotherapy or any other comprehensive treatment.