论文部分内容阅读
目的探讨皮肌炎/多发性肌炎(DM/PM)合并甲状腺功能异常的临床特点及其意义。方法回顾性分析86例DM/PM患者的甲状腺功能检测指标及其临床资料,依据其甲状腺功能检测结果是否正常进行分组、比较。结果 86例DM/PM患者中,甲状腺激素检测结果异常者54例(62.79%);其中甲状腺机能正常的病态综合征发生率最高(51.85%),其他依次为亚临床甲减、临床型甲减、亚临床甲亢、桥本甲状腺炎。与正常组相比,甲状腺激素异常组患者多见合并发热、胸膜炎/胸腔积液,也常出现CRP升高、低蛋白血症、血钙下降(P均<0.05)。结论 DM/PM患者合并甲状腺激素异常的发生率高,其中尤以甲状腺机能正常的病态综合征最为多见。
Objective To investigate the clinical features and clinical significance of dermatomyositis / polymyositis (DM / PM) complicated with thyroid dysfunction. Methods A retrospective analysis of 86 cases of DM / PM thyroid function test indicators and clinical data, according to their thyroid function test results were normal grouping, comparison. Results Of the 86 patients with DM / PM, 54 (62.79%) had abnormal results of thyroid hormone test, the highest incidence of sick syndrome with normal thyroid function was 51.85%, the other were subclinical hypothyroidism, clinical hypothyroidism , Subclinical hyperthyroidism, Hashimoto’s thyroiditis. Compared with the normal group, patients with abnormal thyroid hormone group were more common fever, pleurisy / pleural effusion, also often increased CRP, hypoproteinemia, serum calcium decreased (P all <0.05). Conclusion DM / PM patients with high incidence of thyroid hormone abnormalities, especially in normal thyroid dysfunction syndrome most common.