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PN支持治疗食管、贲门癌术后吻合口瘘患者17例,食管癌12例,贲门癌5例,PN治疗后13例被治愈(766%),3例死亡(17.6%)。吻合口愈合时间最短7天,最长41天,50%PN组患者治疗后7~15天内瘘趋于愈合。50%水、电解质及负氮平衡在PN治疗后3~5天得到迅速纠正,平均氮平衡为2.3g/日(+1.5g~+3.0g),总蛋白有所提高,治疗前后白细胞比值有显差异(P<0.05)。PN支持可能提高吻合口瘘愈合率,可能为降低死亡率的有效手段(P<0.001)。
PN supported 17 patients with anastomotic fistula after esophageal or cardiac cancer surgery, 12 with esophageal cancer, 5 with cardia cancer, 13 after PN treatment were cured (766%), and 3 died (17.6%). The shortest healing time of anastomosis was 7 days, and the longest was 41 days. In 50% PN group, the tendon healed within 7-15 days after treatment. 50% water, electrolytes and negative nitrogen balances were rapidly corrected 3 to 5 days after PN treatment. The average nitrogen balance was 2.3g/day (+1.5g to +3.0g), total protein was increased, and the ratio of leukocytes before and after treatment was improved. There was a significant difference (P<0.05). PN support may increase the healing rate of anastomotic fistulas and may be an effective means of reducing mortality (P<0.001).