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单克隆抗体以其特异性强、均～性好的特点在疾病治疗中已显示了良好的应用前景，但由f目前所用单抗多为鼠源性抗体，进行治疗时，由f多次使用或多剂量使用，会刺激人体产生抗鼠抗体（HAMA）的排斥反应，这不仅减弱了单抗的治疗效果，而且还会使人体产生其它副反应，从而阻碍了
Monoclonal antibody has shown a good application prospect in the treatment of diseases due to its strong specificity and good specificity. However, most of the monoclonal antibodies currently used by mice are murine antibodies and are frequently used by f Or multiple doses will stimulate the body to produce anti-mouse antibody (HAMA) rejection, which not only reduces the therapeutic effect of monoclonal antibody, but also make the body produce other side effects, thus impeding the