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作者观察21例50岁以下的甲状腺功能亢进(甲亢)病人的维生素 D 代谢。患者每日早晨1次口服甲亢平30mg,前3周同时口服心得安40mg,每日3次。随访18个月以上。每3周查1次血清钙、磷、肌酐、碱性磷酸酶、白蛋白、T_3及 T_4浓度等。并在治疗前、治疗后甲状腺功能正常时及 TSH 对静脉注入200μgTRH 反应阳性时测定血清25(OH)D_3、24,25(OH)_2D_3和1,25(OH)_2D_3。以26名正常人作对照。结果①甲亢病人血清钙、磷及碱性磷酸酶轻度增高,而免疫反应性甲状旁腺激素(iPTH)浓度降低。②甲亢病人在治疗前、后血清25(OH)D_3浓度无
The authors observed the vitamin D metabolism in 21 patients under 50 years of age with hyperthyroidism (hyperthyroidism). Patients in the morning daily oral hyperthyroidism flat 30mg, the first 3 weeks oral propranolol 40mg, 3 times a day. Follow-up more than 18 months. Check every 3 weeks of serum calcium, phosphorus, creatinine, alkaline phosphatase, albumin, T_3 and T_4 concentrations. Serum 25 (OH) D_3,24,25 (OH) _2D_3 and 1,25 (OH) _2D_3 were measured before treatment, after thyroid function was normal, and TSH was positive for intravenous injection of 200μgTRH. Take 26 normal people as control. Results ① Serum calcium, phosphorus and alkaline phosphatase were slightly increased in patients with hyperthyroidism, while the concentration of immunoreactive parathyroid hormone (iPTH) was decreased. ② hyperthyroidism patients before and after treatment serum 25 (OH) D_3 concentration without