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三阴性乳腺癌（ TNBC）是一种高度异质性的疾病。因缺乏有效的治疗靶标，故临床预后较差。尽管大量文献报道肿瘤浸润淋巴细胞与TNBC预后之间的关系，但区分不同类型的T淋巴细胞极其重要，因为他们在肿瘤微环境中发挥着不同的作用。此外，有研究发现肿瘤相关巨噬细胞与TNBC预后不良相关。本文将对不同淋巴细胞浸润在TNBC临床预后中的作用作一综述。“,”Triple-negative breast cancer( TNBC) is a heterogeneous disease. It is often characterized by the lack of specific therapeutic molecular targets and poor prognosis. There are increasing evidences about the relationship between tumor-infiltrating lym-phocytes and the prognosis of TNBC. However, the distinction between different types of T lymphocytes is extremely important, because of their different roles in the tumor microenvironment. Moreover, tumor-associated macrophages have been associated with a relatively poor outcome in TNBC. In this article, we review the role of different lymphocyte infiltration in the clinical outcome of TNBC.