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外分泌胰腺是目前最难进行研究和检查的器官之一。现有的诊断方法可分二大类:(1)测定胰腺分泌液体的能力;(2)了解胰腺结构的改变。应用最广的胰腺外分泌功能试验是插入十二指肠引流管,给予各种刺激后,测定十二指肠液的容量、重碳酸盐和酶类。刺激剂有促胰液素,胆囊收缩素—促胰酶素,试餐等。Lundh氏试餐法较简单,可以较好地区分正常或病态的胰功能,但有少数小肠粘膜疾患和阻塞性黄疸患者亦可异常。这些方法的最大缺点是需插入十二指肠管,有些病人不能耐受。因此有人提出“无管法”,即在注射胆囊收缩素—促胰酶素后测定粪内胰蛋白酶和糜蛋白酶的排出量,此结果与插管法结果有相关性。某些慢性胰腺炎病人由于胰管不完全性阻塞,于
Exocrine pancreas is one of the most difficult organs to study and examine. The existing diagnostic methods can be divided into two categories: (1) the ability to measure pancreatic secretion of liquid; (2) to understand the changes in pancreatic structure. The most widely used pancreatic exocrine function test is the insertion of a duodenal drainage tube. After various stimulations, the volume of duodenal fluid, bicarbonate and enzymes are measured. Irritant with secretin, cholecystokinin - pancrease, test meal and so on. Lundh ’s simple meal test method can better distinguish between normal or pathological pancreatic function, but a small number of small intestinal mucosa disease and obstructive jaundice patients may also be abnormal. The biggest drawback of these methods is the need to insert duodenal tubes, some patients can not tolerate. Therefore, it was proposed that “tubeless method”, that is, after injection of cholecystokinin-pancreensin determination of excretion of trypsin and chymotrypsin excretion, the results and the intubation results are related. Some patients with chronic pancreatitis due to incomplete obstruction of the pancreatic duct, in