论文部分内容阅读
目的探讨大量输血后患者相关生化指标的变化及临床意义。方法选择2015年4月-2016年4月在本院输血量为2 000 ml~5 000 ml的患者40例作为研究对象,对比分析输血前后电解质(包括Na~+、K~+、Ca~(2+)、Cl~-)、凝血功能[包括凝血时间(PT)、凝血酶原活动度时间(APTT)、出血时间(TT)及纤维蛋白原(Fbg)水平]、血气分析[包括动脉血p H值、血乳酸(Lac)、碱剩余(BE)]指标。结果与输血前比较,BE值增高,Lac值低;输血后K~+水平高于输血前,Ca~(2+)水平低于输血前;输血后患者PT、APTT均大于输血前,上述差异均有统计学意义(P<0.05)。输血前后p H值差异无统计学意义;TT和Fbg输血前后差异无统计学意义(P>0.05)。结论大量输血导致患者内环境变化,需要注意电解质及凝血功能障碍。
Objective To investigate the changes and clinical significance of biochemical markers in patients after massive blood transfusion. Methods Forty patients with blood transfusion from 2000 to 5000 ml in our hospital from April 2015 to April 2016 were selected as the study subjects. The levels of electrolytes (including Na ~ +, K ~ +, Ca ~ (-)) (Including clotting time (PT), prothrombin time (APTT), bleeding time (TT) and fibrinogen (Fbg) levels), blood gas analysis [including arterial blood p H value, lactic acid (Lac), base residue (BE)]. Results Compared with those before transfusion, the value of BE increased and the value of Lac was lower. The level of K ~ + after transfusion was higher than that before transfusion and the level of Ca ~ (2+) was lower than before transfusion. The PT and APTT after transfusion were higher than those before transfusion All were statistically significant (P <0.05). There was no significant difference in p H before and after blood transfusion; there was no significant difference between before and after transfusion of TT and Fbg (P> 0.05). Conclusion A large number of blood transfusion lead to changes in the patient’s internal environment, need to pay attention to electrolytes and coagulation disorders.