原发性头颈黏膜黑色素瘤(PMMs)并不常见,好发于鼻腔、鼻窦及口腔黏膜。主要治疗方法为手术切除,辅助术后放疗。对PMMs的综合治疗尚无深入研究,也未形成标准化。辅助放疗能够降低局部复发率,但不能提高总生存率。口腔PMMs患者建议采取选择性颈淋巴清扫术。对原发灶无法切除及出现远 Primary head and neck mucosal melanoma (PMMs) are uncommon and occur in the nasal cavity, paranasal sinuses and oral mucosa. The main treatment for surgical resection, adjuvant postoperative radiotherapy. The comprehensive treatment of PMMs no further study, nor formed a standardization. Adjuvant radiotherapy can reduce the local recurrence rate, but can not increase the overall survival rate. Patients with oral PMMs recommend selective neck dissection. Unable to remove the primary tumor and appear far