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1976年我们首先将国产厌氧棒状菌苗用于胸部肿瘤手术前治疗并结合临床疗效分析,对84例手术切除之肿瘤组织作病理检查,其中44例作电镜观察。病例中菌苗组35例,对照组49例。有食管癌、贲门癌和肺癌三种。病理分类为鳞癌47例,腺癌25例、未分化癌12例。临床术后追踪观察发现菌苗组之食管癌和贲门癌有减缓复发趋势,肺癌生存期延长明显持久地消退胸水,减轻痛苦。
In 1976, we first used domestic anaerobic coryneform bacterins for preoperative treatment of thoracic neoplasms and combined with clinical efficacy analysis. 84 cases of surgically resected tumor tissue were examined by pathology, 44 of which were used for electron microscopy. There were 35 cases of bacterin in the case and 49 cases in the control group. There are three types of esophageal, cardiac, and lung cancers. Pathological classification included 47 cases of squamous cell carcinoma, 25 cases of adenocarcinoma, and 12 cases of undifferentiated carcinoma. After clinical observation, it was found that esophageal and cardia cancers in the bacteriophage group had a tendency to slow recurrence, and the survival of lung cancer prolonged significantly and persistently to retreat pleural effusion and relieve pain.