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目的：分析骨科创面治疗时使用负压封闭引流术的临床疗效。方法66例有较大创面患者，随机分为对照组和观察组，每组33例。对照组患者实施开放引流术，观察组患者采用负压封闭引流术治疗。观察两组临床疗效。结果观察组患者治疗显效17例，有效15例，无效1例，总有效32例，治疗总有效率96.97%，对照组患者显效13例，有效12例，无效7例，总有效25例，治疗总有效率75.76%，观察组治疗总有效率明显高于对照组，差异有统计学意义(P<0.05)。观察组患者并发症发生率为3.03%，对照组患者并发症发生率为18.18%，观察组患者并发症发生率明显低于对照组，差异有统计学意义(P<0.05)。结论在对骨科有较大创面患者治疗时，使用负压封闭引流术可取得更加安全有效的临床疗效，有较高的临床使用价值。“,”ObjectiveTo analyze clinical effect by vacuum sealing drainage for wound treatment in department of orthopedics.MethodsA total of 66 patients with large wound were randomly divided into control group and observation group, with 33 cases in each group. The control group received open drainage, and the observation group received vacuum sealing drainage for treatment. Clinical effects of the two groups were observed. ResultsThe observation group had 17 excellent cases, 15 effective cases and 1 ineffective case, with 32 total effective cases and total effective rate as 96.97%, and the control group had 13 excellent cases, 12 effective cases and 7 ineffective cases, with 25 total effective cases and total effective rate as 75.76%. The observation group had obviously higher total effective rate than the control group, and the difference had statistical significance (P<0.05). The observation group had incidence of complications as 3.03%, which was 18.18% in the control group. The observation group had much lower incidence of complications than the control group, and the difference had statistical significance (P<0.05).ConclusionImplement of vacuum sealing drainage provides safe and effective clinical effect in treating patients with large wound. This method contains high value for clinical application.