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目的：探讨百令胶囊联合脉血康治疗2型糖尿病早期肾病对患者肾脏生化指标的影响。方法100例2型糖尿病早期肾病患者,采用随机数字表法分为试验组和对照组,每组50例。对照组采用常规治疗,试验组在常规治疗基础上给予百令胶囊联合脉血康治疗,观察两组在治疗前、治疗后6个月、治疗后1年的肾脏生化指标改变情况。结果治疗前试验组24 h尿白蛋白排泄率(UAER)、尿素(UR)、肌酐(Cr)、胱抑素C(CysC)指标分别为(298.7±16.6)mg/d、(7.6±0.9)mmol/L、(164.8±15.8)μmol/L、(2.9±0.9)mg/L,与对照组的(289.6±15.8)mg/d、(7.6±0.8)mmol/L、(170.5±14.9)μmol/L、(2.8±0.9)mg/L比较,差异无统计学意义(P>0.05)。治疗6个月及治疗1年后,两组上述指标均优于治疗前,差异有统计学意义(P<0.05)；治疗1年后,试验组UAER、CysC指标优于对照组,差异有统计学意义(P0.05). In 6 months and 1 year after treatment, both groups had better indexes than those before treatment, and the difference had statistical significance (P<0.05). In 1 year after treatment, the experimental group had better UAER and CysC than the control group, and the difference had statistical significance (P<0.05).ConclusionCombination of Bailing capsules and Maixuekang capsules in treating type 2 early diabetic nephropathy can remarkably improve early symptoms in patients, and it is better than conventional therapy.