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近年来的研究表明,HBV-DNA不仅存在于肝组织中,而且在许多肝外组织如白细胞中也可被检测到。作者为了研究在不同条件下HBV感染后的白细胞HBV-DNA存在的频率,是否存在对HBV敏感的特定的白细胞表型,以及白细胞HBV-DNA的大小是否与病毒的复制有关,对53例急性和慢性HBV感染者外周血中不同类型白细胞的HBV-DNA存在状态进行了分析。
Recent studies have shown that HBV-DNA is not only found in liver tissue, but also in many extrahepatic tissues such as leukocytes. The aim of this study was to investigate the presence of HBV-DNA in HBV infected lentivirus under different conditions, whether there is a specific white blood cell phenotype sensitive to HBV, and whether the size of leucocyte HBV-DNA is related to the replication of the virus. The status of HBV-DNA in different types of white blood cells in peripheral blood of patients with chronic HBV infection was analyzed.