建立了原子吸收光谱法测定药片中磺胺甲恶唑的方法。样品经微波消解处理后,加入过量Pb2+生成沉淀,然后采用原子吸收分光光度法测定剩余的Pb2+,从而间接测定磺胺甲恶唑(SMZ)的含量。该方法的平均回收率为96.3%—104.4%,相对标准偏差(RSD)小于4.85%。研究表明,该法适用于磺胺甲恶唑含量的测定。方法简便快速,准确。 A method for the determination of sulfamethoxazole in tablets by atomic absorption spectrometry was established. Samples were digested with microwaves and excess Pb2 + was added to precipitate. The remaining Pb2 + was determined by atomic absorption spectrophotometry to determine the content of sulfamethoxazole (SMZ) indirectly. The average recoveries of this method were 96.3% -104.4% with relative standard deviations (RSDs) less than 4.85%. Studies have shown that this method is suitable for the determination of sulfamethoxazole. The method is simple, fast and accurate.