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目的:了解女性生殖道感染抗生素应用现况,为生殖道感染的医疗保健服务提供基础资料。方法:以整群抽样方法抽取兰州市四所医院(1所省级专科医院、3所省级综合医院)2003年度女性生殖道感染住院病历,查阅医嘱、对抗生素应用情况进行回顾性资料分析。结果:女性生殖道感染住院病例抗生素使用率100%,使用品种52种,使用频率居前3位者为甲硝唑(38·25%)、头孢噻肟钠(13·51%)、环丙沙星(11·64%)。首次用药抗生素使用率100%,使用品种41种,使用频率居前3位者为甲硝唑(31·99%)、环丙沙星(26·80%)、头孢噻肟钠(21·04%);抗生素联合用药占36·17%,且专科医院较综合医院高(P<0·05),给药途径以静脉点滴(97.19%)为主;抗生素不合理应用形式多样,其中以给药次数过少(54·71%)、联合过多(17·05%)、配伍不当(12·94%)较为突出;无药敏选药率达84%~100%。结论:女性生殖道感染治疗中抗生素使用率高,用药种类选择范围集中;药敏试验率低;存在不合理应用抗生素的现象。需严格规范临床抗生素的应用,提高用药水平,促进妇女生殖健康。
OBJECTIVE: To understand the status of antibiotics used in female genital tract infections and provide basic information for health care services for genital tract infections. Methods: The hospitalized medical records of female genital tract infection in four hospitals in Lanzhou (1 provincial specialized hospital and 3 provincial general hospitals) were drawn by cluster sampling method. The medical records were read and the application of antibiotics was retrospectively analyzed. Results: The prevalence of antibiotics in female reproductive tract infections was 100% in hospitalized patients, of which 52 species were used. The top three frequency of use was metronidazole (38.25%), cefotaxime sodium (13.51%), Shaxing (11.64%). The first-time use of antibiotics was 100% and 41 varieties were used. The top three users were metronidazole (31.99%), ciprofloxacin (26.80%) and cefotaxime sodium (21.04 %). The antibiotic combination accounted for 36.17%, and the specialty hospitals were higher than general hospitals (P <0.05). The route of administration was mainly intravenous drip (97.19%). The irrational use of antibiotics varied from The number of drugs was too low (54.71%), combined too much (17.05%), improper compatibility (12.94%) was more prominent; drug-free drug selection rate of 84% to 100%. Conclusion: The use rate of antibiotics in female reproductive tract infections is high, the range of choice of drugs is centralized, the rate of drug susceptibility test is low, and there is an irrational use of antibiotics. The need to strictly regulate the application of clinical antibiotics to improve the level of medication to promote women’s reproductive health.