The concept of metamorphic mechanism is put forward according to the change of configurations from one state to another. Different configurations of metamorphic mechanism are described through the method of Huston lower body arrays. Kinematics analyses for metamorphic mechanism with generalized topological structure, including the velocity, angular velocity, acceleration and angular acceleration, are given. Dynamic equations for an arbitrary configuration, including close-loop constraints, are formed by using Kane’s equations. For an arbitrary metamorphic mechanism, the transformation matrix of generalized speeds between configuration ζ and ζ+1 is obtained for the first time. Furthermore, configuration-complete dynamic modeling of metamorphic mechanism including all configurations is completely established. The concept of metamorphic mechanism is put forward according to the change of configurations from one state to another. Different configurations of metamorphic mechanisms are described through the method of Huston lower body arrays. Kinematics analyzes for metamorphic mechanism with generalized topological structures, including the velocity, Dynamic equations for an arbitrary configuration, including close-loop constraints, are formed by using Kane’s equations. For an arbitrary metamorphic mechanism, the transformation matrix of generalized speeds between configuration ζ and ζ + 1 is obtained for the first time. Furthermore, configuration-complete dynamic modeling of metamorphic mechanisms including all configurations is completely established.