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目的:证实针刺治疗慢性疼痛所致抑郁症的有效性,并分析其优势.方法:按随机数字表法将患者随机分为针刺治疗组、西药组,分别接受针刺、抗抑郁药(黛力新)抗抑郁治疗.治疗前后两组患者均采用汉密尔顿抑郁量表(HAMD)和疼痛模拟评分(VAS)分别在治疗前及治疗后第1、2、4周末进行评定.结果:①针刺组治疗前后HAMD、VAS评分、HAMD减分率比较均有极其显著性差异.(P<0.01).②西药组治疗前后HAMD、VAS评分、HAMD减分率比较均有极其显著性差异.(P<0.01).③治疗后1周,针刺组和西药组组间比较HAMD减分率*及VAS评分**均有显著性差异.(*P<0.01,**P0.05).⑤治疗前后针刺组无不良反应,西药组有不良反应发生.结论:针刺和抗抑郁药黛力新治疗慢性疼痛所致抑郁症均有确切疗效,针刺疗效和黛力新相当,但针刺起效快.针刺治疗相对于西药治疗无副作用、无不良反应,并且针刺治疗可以多靶点对机体进行整体调整.“,”Objective To study and verify the efficacy of acupuncture on depression caused by chronic pain and to further analyze the advantages of acupuncture. Methods According to random number table, the cases were randomized into experimental group and western medicine group, treated with acupuncture and anti-depression drug (deanxit) respectively. Hamilton Depressive Scale (HAMD) and Visual Analogue Scale (VAS) were adopted for the evaluation before treatment and in the 1, 2 and 4 weeks after treatment in two groups successively. Results ① Very significant differences had been achieved on the comparisons of HAMD, VAS and HAMD reducing rate before and after treatment in experimental group (P<0.01). ② Very significant differences had been achieved in the comparisons of HAMD, VAS and HAMD reducing rate before and after treatment in western medicine group (P<0.01). ③ Significant differences in HAMD reducing rate* and VAS score**had been achieved in the comparison between experiment group and western medicine group 1 week after treatment (*P<0.01, **P0.05). ⑤ No any harmful effect happened in experimental group after treatment, but it happened in western medicine group. Conclusion Both acupuncture and deanxit have achieved the definite therapeutic effects on depression caused by chronic pain, with similar efficacy. But the effects of acupuncture are obtained more quickly. In comparison of western medicine, acupuncture has no side and harmful effect. Additionally, acupuncture applies the multi-targeting and holistic modulation to the whole body.