在淋巴细胞分化、成熟以及受抗原刺激而发挥其机能的过程中,细胞内酶和代谢方面的变化起着很大的作用,这可由临床上的事实得知:先天性免疫不全症患者可伴有酶的缺陷;使用阻碍核酸合成药物或影响环状核苷酸水平的药物等时,均可看到伴随着淋巴细胞机能的变化。以下就几个方面叙述最近的发现:1、酶缺陷症与淋巴细胞分化障碍腺嘌呤核苷脱氨酶(ADA)是腺嘌呤核 Changes in intracellular enzymes and metabolism play a large role in lymphocyte differentiation, maturation, and antigen-stimulated functioning, as evidenced by clinical evidence that patients with congenital immunodeficiency syndrome may be associated There are enzyme defects; use of drugs that hinder nucleic acid synthesis drugs or affect the level of cyclic nucleotides, etc., can be seen with changes in lymphocyte function. The following is a description of recent findings in several areas: 1, enzyme deficiency and lymphocyte dysplasia adenosine deaminase (ADA) is adenine nucleus