本文报道了胆红素和胆绿素 ,以及氧化胆红素的 SERS谱图。通过对其谱图的分析发现 ,氧化胆红素SERS谱与胆绿素 SEES谱极其相近。表明胆红素在碱性环境中可被氧化成胆绿素。另外 ,通过对比胆红素和胆绿素的 SERSS谱 ,发现在银胶界面它们的吸附构象不同 This article reports the SERS spectra of bilirubin and biliverdin, and oxidized bilirubin. Through the analysis of its spectrum, we found that the SERS spectrum of oxidized bilirubin is very similar to the SEES spectrum of bilirubin. Bilirubin is shown to be oxidized to biliverdin in an alkaline environment. In addition, by comparing the SERSS spectra of bilirubin and biliverdin, it is found that their adsorption conformations are different at the silver glue interface