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在原发性肝癌的诊断中,约有20％左右的甲胎蛋白是阴性的,作者选用五酶同侧法以诊断原发性肝癌,效果良好。检查甲胎蛋白阴性原发性肝癌(65例)的酶谱值及阳性率都高于非肝癌组(50例),并有显著性差异(P<0.01)。其中有11例经手术切除,病检证实为分化型和低分化型肝细胞癌,从而进一步证实上述酶的指标是一组敏感的肝癌标记物。五酶同测法有利于提高AFP阴性肝癌的诊断,方法简
In the diagnosis of primary liver cancer, about 20% of alpha-fetoprotein is negative. The authors selected the five-enzyme ipsilateral method for the diagnosis of primary liver cancer with good results. The zymogram and positive rate of alpha-fetoprotein-negative primary liver cancer (65 cases) were higher than those of non-hepatoma group (50 cases), and there was a significant difference (P<0.01). Among them, 11 cases were surgically resected. The pathological examination confirmed differentiated and poorly differentiated hepatocellular carcinoma, which further confirmed that the above-mentioned enzyme index is a group of sensitive liver cancer markers. Five-enzyme-analyzed assay is helpful to improve the diagnosis of AFP-negative liver cancer.