1病例报告患者女,51岁。步态不稳、歪斜11年余。患者于11年前无明显诱因出现步态不稳,症状轻微,独立行走无歪斜,偶伴头晕。此后逐渐出现行动缓慢、不能直线行走、频繁摔倒、双眼睑不自主颤动、言语不清、吞咽困难、饮水呛咳、视物模糊、近事遗忘、记忆力明显减退,生活不能自理? 1 case report Patient female, 51 years old. Gait instability, skew more than 11 years. Patients 11 years ago, there was no obvious incentive to instability gait, minor symptoms, independent walking without skew, accompanied by dizziness. Since then gradually slow action, can not be a straight line, frequent falls, involuntary involuntary flutter in both eyelids, speechless, swallowing difficulties, drinking cough, blurred vision, recent forgetting, memory loss, life can not take care of themselves?