论文部分内容阅读
目的对比分析超声引导下细针穿刺组织学检查联合细胞块免疫组织化学与粗针组织学检查对于诊断浅表淋巴结疾病的临床应用价值。方法选取淋巴结病变患者75例,超声引导下分别采用25G细针及18G活检针穿刺取材,所获得标本分别送细胞学检查结合细胞块免疫组织化学以及组织学检查结合免疫组织化学检测。对两者的诊断结论并结合随访结果进行回顾性分析及对比。结果本组病例细针穿刺取材成功率为93.3%(70/75),粗针穿刺取材成功率为96.0%(72/75)。70例细针穿刺患者中,64例细胞学检查与细胞块免疫组织化学联合诊断结果与随访结果相符,临床诊断符合率为91.4%(64/70)。72例粗针穿刺患者中,67例组织学检查结合免疫组织化学联合诊断结果与随访结果相符,临床诊断符合率为93.1%(67/72)。两种不同方法检测结果比较,其穿刺取材成功率及临床诊断符合率差异无统计学意义(P>0.05)。结论超声引导细针抽吸细胞学检查联合细胞块免疫组织化学诊断浅表淋巴结病变简便实用、安全可靠,与粗针组织学检查的临床诊断符合率无差异。
Objective To compare and analyze the clinical value of ultrasonography guided fine needle aspiration biopsy combined with cell mass immunohistochemistry and gross needle histology in the diagnosis of superficial lymph node disease. Methods Totally 75 patients with lymphadenopathy were selected. Under the guidance of ultrasound, 25G fine needle and 18G biopsy needle were taken respectively. The specimens were sent for cytological examination combined with immunohistochemistry and histological examination with immunohistochemistry. The conclusions of the two diagnosis and follow-up results were retrospectively analyzed and compared. Results The successful rate of fine needle aspiration was 93.3% (70/75) in this group, and 96.0% (72/75) in needle aspiration. Among the 70 cases of fine-needle aspiration, 64 cases of cytology combined with immunohistochemistry were consistent with the results of follow-up. The coincidence rate of clinical diagnosis was 91.4% (64/70). Of the 72 patients who underwent needle puncture, the 67 cases combined histological examination and immunohistochemistry were consistent with the follow-up results. The coincidence rate of clinical diagnosis was 93.1% (67/72). There was no significant difference in the success rate of puncture and clinical coincidence between two different methods (P> 0.05). Conclusion Ultrasound-guided fine needle aspiration cytology combined with immunohistochemistry of cell mass in the diagnosis of superficial lymph node lesions is simple and practical, safe and reliable, and there is no difference in the coincidence rate with clinical diagnosis of thick needle histology.