多发性骨髓瘤（ＭＭ）是浆细胞异常增生的恶性肿瘤，常见症状为骨骼疼痛、反复感染等，以脊髓短暂性缺血发作为首发症状少见，现报告１例。１　病例介绍患者，男，７８岁。因间断性双下肢无力１个月于１９９９年２月３日收入院。１个月来在活动中出现双下肢无力，抬腿困难，约 Multiple myeloma (MM) is a malignant tumor of plasma cell dysplasia. The common symptoms are bone pain and repeated infections. Spinal cord transient ischemic hair is rarely seen as the first symptom. One case is now reported. 1 case presentation patient, male, 78 years old. He was admitted to the hospital on February 3, 1999 due to intermittent weakness in both lower limbs for 1 month. In the past one month, there was weakness in both legs and difficulty in lifting his legs.