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头颈部肿瘤的浸润性淋巴细胞,不仅具有特异、高效的杀瘤活性,而且具有依赖IL-2低、副作用小等优点。是近年基础和临床方面研究的热点课题之一,该细胞被认为是继LAK细胞之后第二代抗瘤效应细胞。本文概要综述其在头颈部肿瘤方面的实验研究和应用前景。
Invasive lymphocytes of head and neck tumors not only have specific and highly efficient tumoricidal activity, but also have the advantages of low IL-2 dependency and small side effects. It is one of the hot topics in basic and clinical research in recent years. This cell is considered to be the second generation of anti-tumor effector cells following LAK cells. This article summarizes its experimental research and application prospects in head and neck cancer.