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本文报告交联琼脂糖包膜活性炭(CAAC)对某些中毒性药物及与肝性脑病发病可能有关的代谢产物如r-氨基丁酸、内毒素、氨基酸等的体外吸附作用。实验证明对此类物质均有不同程度的吸附功能,符合医用吸附剂的要求,对于肝性脑病血液灌流治疗的开展,特别是急性药物中毒血液灌流的临床应用提供了一定的理论依据。
This article reports the in vitro adsorption of certain toxic drugs and the possible metabolites such as r-aminobutyric acid, endotoxins and amino acids by cross-linked agar coated activated carbon (CAAC) on hepatic encephalopathy. Experiments show that these substances have different degrees of adsorption, in line with the requirements of medical adsorbents, for Hepatic Encephalopathy Hemoperfusion treatment, especially the clinical application of acute drug poisoning hemoperfusion provides a theoretical basis.