论文部分内容阅读
目的探讨新生儿化脓性脑膜炎的早期临床特点和干预措施。方法选择2010年1月至2011年12月新生儿科收治的化脓性脑膜炎患儿18例进行回顾性分析。结果新生儿化脓性脑膜炎在发病初期多有体温异常(发热或体温不升),哭声弱或呻吟,呼吸暂停,肌张力改变,前囟紧张或饱满等,血白细胞总数未见明显异常现象,CRP增高占72.2%,脑脊液白细胞和蛋白均增高,葡萄糖≥2.2mmol/L3例占16.79%,病原菌主要是葡萄球菌,大肠埃希菌。结论新生儿化脓性脑膜炎在发病早期临床表现不典型,尽早行脑脊液检查,及时合理应用抗生素是治疗关键。
Objective To investigate the early clinical features and interventions of neonatal purulent meningitis. Methods 18 cases of purulent meningitis admitted to neonatology department from January 2010 to December 2011 were retrospectively analyzed. Results Neonatal purulent meningitis in the early onset of abnormal body temperature (fever or body temperature does not rise), cry weak or moaning, apnea, muscle tone changes, anterior fontanel tension or fullness, the total number of white blood cells showed no significant abnormalities , CRP increased 72.2%, cerebrospinal fluid leukocyte and protein were increased, glucose ≥ 2.2mmol / L3 cases accounted for 16.79%, the main pathogens are Staphylococcus aureus, Escherichia coli. Conclusion neonatal purulent meningitis in the early onset of clinical manifestations atypical early as early cerebrospinal fluid examination, timely and rational use of antibiotics is the key to treatment.