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目的:研究慢性阻塞性肺病(COPD)患者进行体外隔肌起搏(EDP)长程治疗对肺功能的影响。方法:30例接受EDP2周治疗的COPD稳定期住院患者,出院后随机分为家庭继续EDP治疗组(继治组)和停止治疗组(停治组),每组各15例,分别在治疗前、治疗2周、治疗(或停治)6周及16周测定通气功能及6分钟行走距离(6MWD)。结果:2周EDP治疗显示肺活量(VC)、第1秒用力呼气容积(FEVI)、第1秒用力呼气容积占用力肺活量百分卜匕(FEVI/FVC)、最大通气量(MVV)和6MwD均有显著提高(P<0.“),继治组6周{。1(涵上述指标仍有进一步提高(尸<0.05),而停治组其疗效逐渐减退至恢复到治疗前水平(l’。门;)、结论:长程EDP治疗是提高COPD患者肺功能和全身活动状况的有效方法之一。
OBJECTIVE: To investigate the effects of long-term diaphragmatic pacing (EDP) on pulmonary function in patients with chronic obstructive pulmonary disease (COPD). Methods: Thirty COPD stable patients undergoing EDP for 2 weeks were randomly divided into family continuation EDP treatment group (follow-up group) and stop treatment group (stop treatment group), 15 cases in each group. Before treatment , 2 weeks of treatment, ventilation (6MWD) and 6 minutes of ventilation (6MWD) at 6 weeks and 16 weeks of treatment (or discontinuation). Results: Two weeks of EDP showed that the vital capacity (VC), FEV 1, FEV 1, MVV and 6MwD were significantly increased (P <0. ”), following the rule group 6 weeks {.1 Han (these indicators are still further improved (P <0.05), while the treatment group gradually reduced its efficacy to restore treatment Before the level (l ’; door;), Conclusion: Long-term EDP treatment is to improve lung function and systemic activity in COPD patients with an effective method.