邵××女生后1天门诊号45118于1987年6月8日出生,第一胎、足月、自然分娩,出生时发现左眼畸形,于生后14小时来诊。患儿体重3.4kg,发育良好,头、颈、胸、肤、四肢均正常。右眼未见异常,左眼角膜自角膜缘呈圆锥形凸出睑裂之外(图1)。触之柔软,拉开眼睑,可窥见少许球结膜,无充血。左眼角膜呈浅蓝色混浊。于生后52天,左眼角膜自行破溃,流出黄绿色液体, Shao XX girls 1 day after the clinic No. 45118 was born on June 8, 1987, the first child, term, natural childbirth, birth was found left eye deformity, 14 hours after birth to the clinic. Children weighing 3.4kg, well-developed, head, neck, chest, skin, limbs are normal. There was no abnormality in the right eye, and the cornea of ​​the left cornea showed a conical bulging from the corneal margin (Figure 1). Touch the soft, open the eyelid, can see a little ball conjunctiva, no congestion. Left corneal pale blue turbid. 52 days after birth, the left cornea ulceration, shed yellow-green liquid,