目的探讨内镜、腹腔镜在胃间质瘤治疗中的应用价值。方法回顾性分析46例胃间质瘤患者微创治疗的临床资料。其中,内镜组23例,腹腔镜组10例,双镜联合组13例。结果内镜组病灶均成功切除,1例术后13h出现胃出血;单纯腹腔镜组病灶均成功切除,1例术后第3天出现肠梗阻;双镜联合切除13例,无术后并发症发生。随访3-48个月,内镜组2例复发,单纯腹腔镜组及双镜联合组无复发病例。三组均无死亡病例。免疫组化结果:CD117阳性41例(89.1%),CD34阳性32例(69.6%)。结论与单用内镜或腹腔镜相比,双镜联合应用在胃间质瘤的治疗中具有较高的安全性及有效性。 Objective To investigate the value of endoscopy and laparoscopy in the treatment of gastric stromal tumors. Methods Retrospective analysis of 46 cases of gastric stromal tumor minimally invasive treatment of clinical data. Among them, 23 cases of endoscopic group, laparoscopic group of 10 cases, 13 cases of double mirror combination group. Results All the lesions in the endoscopic group were successfully resected. One case had gastric hemorrhage at 13 hours after operation. All the lesions were successfully resected in laparoscopic group. One case showed intestinal obstruction on the 3rd day after operation. Thirteen cases were removed by double mirror combined with no postoperative complications occur. Follow-up 3-48 months, two cases of endoscopic recurrence, simple laparoscopic and double mirror combined group no recurrence. No deaths were reported in all three groups. The results of immunohistochemistry: CD117 positive in 41 cases (89.1%), CD34 positive in 32 cases (69.6%). Conclusion Compared with single endoscopy or laparoscopy alone, the combination of dual mirror in the treatment of gastric stromal tumors with high safety and effectiveness.