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作者系统的研究了 CC—1065对细胞周期的作用。通过实验研究证实 CC—1065是最有效的抗肿瘤剂。它对 B_(16)细胞和 CHO 细胞及各种人体肿瘤,在单克隆分析中的致死量为1ng/ml。同时,CC—1065亦抑制 DNA 的合成与 DNA 的基因整合。就 CC—1065主要抑制 DNA 合成的动
The author systematically studied the effect of CC-1065 on the cell cycle. CC-1065 proved to be the most effective anti-tumor agent through experimental studies. It has a lethal dose of 1 ng/ml in monoclonal analysis for B_(16) cells and CHO cells and various human tumors. At the same time, CC-1065 also inhibited DNA synthesis and DNA gene integration. CC-1065 mainly inhibits DNA synthesis