核黄素不足和缺乏症为我国常见及分布较广的疾病;蛋白质营养不良也时有报告。二者同时出现于临床患者也非罕见。至于二者间的相互关系,在文献中虽早有记载,但主张颇不一致:Fixsen氏、Kon氏认为核黄素缺乏对於氮平衡代谢并无影响;而印度的Basu同Nath二氏和美国的Kleibe同Jukes二氏,Mayfield同Hedrick Deficiency and deficiency of riboflavin is a common and widely distributed disease in our country; protein malnutrition is also sometimes reported. It is not uncommon for both to appear in clinical patients. As for the relationship between the two, although documented in the literature, but the assertion is quite inconsistent: Fixsen’s, Kon that lack of riboflavin nitrogen balance metabolism has no effect; and Basu in India with Nath and the United States Kleibe with Jukes II, Mayfield with Hedrick