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我科1984～1986年采取鞘内大剂量注射精制破伤风抗毒素(TAT),在门诊共治疗6例破伤风,取得满意效果,现报告如下。临床资料男4例,女2例;年龄最小12岁,最大72岁。除1例2年前曾有破伤风抗毒素预防注射史外,其余5例均无破伤风抗毒素及类毒素注射史。按传染病学分型标准分型,轻型4例,中型2例。鞘内注射TAT前,先作TAT皮试,肌肉注射安定10毫克。采取常规腰穿方法,腰穿成功后,在注射TAT时,要注射与回抽交替进行,即脊髓按摩。TAT用量,成人30,000单位/次,儿童4,500单
Our department from 1984 to 1986 to take intrathecal injection of high-dose tetanus antitoxin (TAT), outpatient treatment of 6 cases of tetanus, and achieved satisfactory results, are as follows. Clinical data of 4 males and 2 females; the youngest 12 years old, maximum 72 years old. In addition to a case 2 years ago had tetanus antitoxin prophylaxis injection history, the remaining 5 cases were not tetanus antitoxin and toxoid injection history. According to the genotyping standard of infectious diseases, 4 cases were light and 2 cases were medium. Intrathecal injection of TAT before TAT skin test, intramuscular injection of 10 mg stability. To take the conventional lumbar puncture method, after the success of lumbar puncture, injection of TAT, to be injected and withdrawn alternately, that spinal cord massage. TAT dosage, adult 30,000 units / time, children 4,500 single