Based on land-use database updated with the survey of 1996, 2000, 2004 and 2008, this paper analyzed the land-use changes in the typical transect area along National Highway 106 with the aid of GIS technology and quantitative models. The results showed that arable land had been continuously decreased from 1996 to 2008, with a loss of 65.85× 10^3 hm2 and an average decrement of 5.49×10^3 hm^2 per year, and the loss in northern areas was larger; garden land and woodland were gradually centralized to the predominance area with an increment of 25.73×10^3 hm2 and 22.37×10^3 hm2, respectively; residential and industrial land increased year after year, and the transportation land showed the equalized developing spatial pattern; the increment of construction land and encroachment on arable land in the area were deeply influenced by the national macroscopic land-use policies, the rapid advance of urbanization and the development level of the regional economy. Through this case study, it is suggested that differential land- use policies should be adopted to create good environmental conditions to guarantee food security and to promote the economic development.