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前列腺增生症(BPH)的病理学特征为腺体和间质的结节状增生。肥大细胞(mast cell,MC)作为组织中一个重要的细细群,在机体的生理和一些病理过程中有重要意义。BPH中肥大细胞的分布及其意义文献中尚鲜见报告。本文用特染及免疫组化方法分别对BPH中肥大细胞及腺上皮人类白细胞Ⅱ类抗原(HLA-DR)表达进行了观察。对BPH中肥大细胞的作用及其与HLA-DR异常表达的关系进行了探讨。
The pathological features of benign prostatic hyperplasia (BPH) are nodular hyperplasia of the gland and stroma. Mast cells (mast cells, MC) as an important group of thin, in the body’s physiological and some pathological process is of great significance. The distribution and significance of mast cells in BPH are rare in the literature. In this paper, special dye and immunohistochemistry were used to detect the expression of human leukocyte antigen (HLA-DR) in mast cells and glandular epithelial cells in BPH. The role of mast cells in BPH and its relationship with the abnormal expression of HLA-DR were discussed.