应用环糊精(CD)作为人工酶模型已经在许多有机反应中显示出特异的结果。CD催化下的合成虽然报道还不多,但已被视为一种有前途的仿生合成。鉴于α,β-环氧酮是一类重要的合成中间体,光学活性的α,β-环氧酮的不对称合成更是人们感兴趣的领域,因而我们研究了如下的在β-CD催化下的Darzens缩合: The use of cyclodextrin (CD) as an artificial enzyme model has shown specific results in many organic reactions. Though CD-catalyzed synthesis is not reported yet, it has been considered as a promising biomimetic synthesis. As α, β-epoxy ketone is an important class of synthetic intermediates, the asymmetric synthesis of optically active α, β-epoxy ketones is still an area of ​​interest. Therefore, Darzens condensation under: