自从10年前开始研究经血管转基因以来,研究人员已取得了显著的成就。目前人体的临床试验也已在进行中,应用血管壁转基因治疗各种血管病已成为可能。但目前所用来源大多为动物动脉,所以还需要在与人更接近或更能代表人的模型或人体的实验中得到验证。动脉粥样硬化是一种复杂疾病,血管转基因治疗可对动脉粥样硬化本身或针对它造成的严重后果(如血栓形成及缺血)进行针对性治疗。 Researchers have made significant achievements since they began researching transmembrane gene transgenesis 10 years ago. The current human clinical trials are already underway, the application of transvascular vascular wall therapy of various vascular disease has become possible. However, most of the sources currently used are animal arteries, so experiments in models or human bodies that are closer to or more representative of human beings need to be verified. Atherosclerosis is a complex disease that is targeted for the treatment of atherosclerosis itself or the serious consequences of it (such as thrombosis and ischemia).