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目的:分析良性阵发性位置性眩晕(BPPV)患者的超声骨密度结果,探讨BPPV与骨密度的关系。方法:实验组为在北京市仁和医院耳鼻咽喉科就诊并符合纳入标准的BPPV患者88例,对照组选择年龄、性别匹配且在1年内无眩晕主诉的健康志愿者76例。2组均进行专科检查、眼震视图检查、位置性试验、超声骨密度检查,根据性别、年龄、听力情况分组。结果:1实验组骨密度T值(-2.010±1.658)明显低于对照组(0.3605±0.875),差异有统计学意义(P<0.01)。2实验组骨量减少35例(39.77%)、骨质疏松26例(29.55%)、骨密度下降61例(69.32%),分别高于对照组的骨量减少13例(17.10%)、骨质疏松6例(7.89%)、骨密度下降19例(25.00%),2组比较差异有统计学意义(P<0.01)。3依年龄分层分组,实验组所有年龄层患者的骨密度值明显低于对照组,并随着年龄增长所呈现的骨密度下降发生率高于对照组,差异有统计学意义(P<0.01)。4在性别分组中发现,实验组女性T值均明显低于对照组,差异有统计学意义(P<0.05);且60岁以后尤其明显。5实验组中骨密度正常的27例患者中听力正常19例(70.37%),听力下降8例(29.63%);61例骨密度下降者中听力正常48例(78.69%),听力下降13例(21.31%)。听力损失与骨密度下降间的差异无统计学意义(P>0.05)。6Logistic回归结果提示骨密度高T值是BPPV的保护因素,OR=0.686(P<0.01,CI:1.32~5.85)。结论:BPPV患者骨密度值低于正常对照组,骨密度下降发生率较高,同时随年龄增加呈上升趋势,女性尤其明显。
OBJECTIVE: To analyze the results of ultrasound bone mineral density in patients with benign paroxysmal positional vertigo (BPPV) and to explore the relationship between BPPV and bone mineral density. Methods: The experimental group consisted of 88 BPPV patients who were admitted to otolaryngology department of Renhe Hospital of Beijing and met the inclusion criteria. The control group included 76 healthy volunteers with age and sex matched and no vertigo complained within one year. 2 groups were specialist examination, nystagmus examination, positional test, ultrasound bone density examination, according to gender, age, hearing grouping. Results: 1 The T value of bone mineral density (-2.010 ± 1.658) in the experimental group was significantly lower than that in the control group (0.3605 ± 0.875), the difference was statistically significant (P <0.01). In the experimental group, 35 cases (39.77%) had osteopenia, 26 cases (29.55%) had osteoporosis, 61 cases (69.32%) had decreased bone density, which were higher than those in the control group 6 cases (7.09%) were osteoporosis and 19 cases (25.00%) were decreased bone mineral density. The difference between the two groups was statistically significant (P <0.01). 3 According to the age stratified group, the BMD values of all age groups in the experimental group were significantly lower than those in the control group, and the incidence of bone mineral density decreased with age was higher than that of the control group (P <0.01 ). 4 In the gender group, the T value of the experimental group was significantly lower than that of the control group, the difference was statistically significant (P <0.05), and especially after 60 years of age. Among the 27 patients with normal BMD, 19 (70.37%) had normal hearing and 8 (29.63%) had hearing loss in 61 patients with normal BMD, 48 (78.69%) had hearing loss in 61 patients with decreased BMD, 13 (21.31%). There was no significant difference between hearing loss and bone mineral density (P> 0.05). The 6Logistic regression results suggested that the high T value of bone mineral density was the protective factor of BPPV, OR = 0.686 (P <0.01, CI: 1.32-5.85). Conclusion: The bone mineral density of patients with BPPV is lower than that of the normal control group, the incidence of bone mineral density decline is higher, and with the increase of age, the female is more obvious.