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采用体外液体培养法，观察不同浓度及不同胎龄人胎肝造血基质细胞条件培养液（ＨＦＬＳＣ－ＣＭ）对ＷＥＨＩ＿３细胞增殖与分化的影响。结果表明：５月龄ＨＦＬＳＣ－ＣＭ能促进ＷＥＨＩ＿３细胞增殖与分化；７月和９月龄ＨＦＬＳＣ－ＣＭ抑制ＷＥＨＩ＿３细胞增殖，促进分化。文中讨论了人胎肝造血基质细胞与造血的关系以及不同时期造血基质细胞的作用。
The effects of HFLSC-CM on the proliferation and differentiation of WEHI 3 cells were observed by liquid culture in vitro. The results showed that HFLSC-CM at 5 months promoted the proliferation and differentiation of WEHI 3 cells. HFLSC-CM at 7 and 9 months inhibited the proliferation of WEHI 3 cells and promoted differentiation. The article discusses the relationship between human fetal liver hematopoietic stromal cells and hematopoiesis and the role of hematopoietic stromal cells in different periods.