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目的探讨不备牙瓷贴面对龈沟液(Gingival crevicular fluid,GCF)中前列腺素E2(Prostaglandin E2,PGE2)和白细胞介素-8(Interleukin-8,IL-8)表达水平的影响。方法选择前牙美容修复患者46例(118颗前牙)随机分为2组,不备牙瓷贴面组(23例52颗前牙)和传统瓷贴面组(23例66颗前牙)分别采用不备牙瓷贴面和传统瓷贴面修复。在修复前、修复后3个月分别用whatmanⅠ号滤纸条吸取龈沟液。采用酶联免疫吸附测定法(ELISA)检测龈沟液中的PGE2和IL-8含量。结果不备牙瓷贴面组在贴面修复后较修复前龈沟液中检测到的PGE2和IL-8含量高,差别有统计学意义。传统瓷贴面组在贴面修复后较修复前龈沟液中检测到的PGE2和IL-8含量有所增加,差别无统计学意义(P>0.05)。不备牙瓷贴面组较传统瓷贴面组在修复后龈沟液中检测到的PGE2和IL-8含量有所增加,差别无统计学意义(P>0.05)。结论两种瓷贴面均可导致龈沟液中PGE2和IL-8水平的变化,对牙周组织有一定的不利影响,且不备牙瓷贴面对牙周组织的影响更大,但不备牙瓷贴面对牙体无预备,符合现代牙体保存学的理念。
Objective To investigate the effect of porcelain veneers on the expression of prostaglandin E2 (PGE2) and interleukin-8 (IL-8) in gingival crevicular fluid (GCF). Methods A total of 46 patients (118 anterior teeth) with cosmetic restoration of anterior teeth were randomly divided into 2 groups without dental veneers (23 with 52 anterior teeth) and traditional porcelain veneers (23 with 66 anterior teeth) Respectively used ceramic veneer and veneer veneer restoration. Before repairing, repaired three months, respectively, whatman number I filter paper sucked gingival crevicular fluid. Enzyme-linked immunosorbent assay (ELISA) was used to detect the levels of PGE2 and IL-8 in gingival crevicular fluid. The results were not prepared dental veneer group after repair in the surface of the gingival crevicular fluid detected before PGE2 and IL-8 content was higher, the difference was statistically significant. In the traditional veneer group, the contents of PGE2 and IL-8 detected in the gingival crevicular fluid after the repair of the veneers were higher than those before the repaired ones, the difference was not statistically significant (P> 0.05). The levels of PGE2 and IL-8 detected in gingival crevicular fluid after repairing were lower than those of traditional porcelain veneer group, which was not statistically significant (P> 0.05). Conclusion Both porcelain veneers can lead to changes of PGE2 and IL-8 levels in gingival crevicular fluid, which may have some adverse effects on periodontal tissues. Moreover, the effects of porcelain veneers on periodontal tissues are not significant Preparation of ceramic veneer on the teeth without preparation, in line with the concept of modern dental preservation.