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目的:探讨新复方党参片对高原士兵脑作业能力和睡眠质量的干预效果,为制定提高高原脑作业能力和睡眠质量方案提供依据。方法:海拔4 100 m高原士兵31人,采用自身配对设计进行试验,比较新复方党参片干预前后高原士兵的脑作业能力和睡眠质量状况。脑作业能力采用神经行为核心测试组合的数字广度、数字译码和目标追踪测试问卷进行评价;睡眠质量状况采用匹兹堡睡眠质量指数量表(PSQI)进行评价。结果:新复方党参片干预对高原士兵的数字广度测试结果无明显影响,干预前后无显著性差异(23.61±2.89 vs 23.23±3.84,P=0.539);新复方党参片干预可提高高原士兵的数字译码能力,干预前后差异有统计学意义(62.03±8.78 vs 72.90±8.08,P<0.01);新复方党参片干预可提高高原士兵的目标追踪的正确数,干预前后差异有统计学意义(119.87±17.65 vs 139.06±38.73,P<0.01);新复方党参片干预前后,高原士兵的睡眠质量状况无明显影响,差异无显著性(6.19±3.44 vs 6.61±4.05,P=0.417)。结论:新复方党参片干预可提高高原士兵脑作业能力而对睡眠质量无明显改善作用,尚需进一步扩大样本量进行深入研究。
Objective: To explore the intervention effect of new compound Codonopsis tablets on brain function and sleep quality of soldiers in plateau, and to provide basis for developing plan of improving brain function and sleep quality in plateau. Methods: 31 soldiers at an altitude of 4 100 m were enrolled in the study. Their self-matching design was used to test the brain function and sleep quality of the plateau soldiers before and after the intervention with the new compound Codonopsis. Brainwork ability was evaluated by digital breadth, digital code and target tracking test questionnaire of neurobehavioral core test combination. Sleep quality status was evaluated by Pittsburgh Sleep Quality Index Scale (PSQI). Results: The new compound Codonopsis intervention had no significant effect on the digital breadth test of soldiers on the plateau, with no significant difference before and after the intervention (23.61 ± 2.89 vs 23.23 ± 3.84, P = 0.539); the new compound Codonopsis intervention could increase the number of plateau soldier (62.03 ± 8.78 vs 72.90 ± 8.08, P <0.01). The new compound Codonopsis intervention could improve the accuracy of target tracking of plateau soldiers, the difference was statistically significant before and after the intervention (119.87 ± 17.65 vs 139.06 ± 38.73, P <0.01). There was no significant difference in the quality of sleep of soldiers in the plateau before and after the new compound Codonopsis intervention (6.19 ± 3.44 vs 6.61 ± 4.05, P = 0.417). Conclusion: The new compound Codonopsis intervention can improve the working ability of the soldiers on the plateau without any significant improvement on the quality of sleep, but we need to further expand the sample size for further study.