为寻找高效、速效、低毒的治疗恶性疟复方 ,采用复方双氢青蒿素 (由双氢青蒿素、磷酸哌喹和甲氧苄啶组成 ) 2天疗程成人总量 8片方案治疗无并发症恶性疟 50例。结果 :平均退热时间为 (17.2± 9.9)h ,平均原虫转阴时间为 (52 .0± 2 0 .2 )h。 4 6例追踪观察 2 8d ,无 1例复燃。 34例患者治疗前检查血液学、丙氨酸氨基转移酶 (ALT)、天门冬酸氨基转移酶 (AST)和总胆红素 ,发现小部分患者有异常改变 ;治疗后7d复查 ,全部患者上述指标均正常 In order to find an effective, quick-acting and low-toxic prescription for the treatment of P. falciparum, compound dihydroartemisinin (consisting of dihydroartemisinin, piperaquine and trimethoprim) 50 cases of falciparum malaria. Results: The mean time to antipyretic fever was (17.2 ± 9.9) h, and the average parasite negative time was (52.0 ± 20.2) h. 46 follow-up observation 28 days, no case of a resurgence. 34 patients before treatment hematology, alanine aminotransferase (ALT), aspartate aminotransferase (AST) and total bilirubin and found that a small part of patients with abnormal changes; review 7d after treatment, all patients in the above The indicators are normal