测定大鼠力竭运动后即刻及恢复期100min时尿中总蛋白(TP)、尿白蛋白(Alb)、尿β2微球蛋白(β2-MG)、尿γ-谷氨酰转肽酶(γ-GT)、N-乙酰-β-D-氨基葡萄糖苷酶(NAG)排泄率,肾脏组织及肾线粒体膜自由基代谢变化及相关性分析。研究表明,力竭运动诱发肾脏组织自由基作用的加强和自由基清除能力的相对不足,导致肾小球滤过膜、肾小管超微结构的改变和功能下降以及肾线粒体膜结构和功能受损、能量代谢障碍,使蛋白质滤过率增加,而肾小管重吸收减少,从而使大鼠力竭运动后尿蛋白排泄率增加。 The urinary total protein (TP), urinary albumin (Alb), urinary β2 microglobulin (β2-MG) and urinary γ-glutamyl transpeptidase (γ) were measured at 100 min after exhaustive exercise -GT), N-acetyl-β-D-glucosaminidase (NAG) excretion rate, free radical metabolism in renal tissue and renal mitochondrial membrane, and correlation analysis. Studies have shown that exhaustive exercise-induced enhancement of free radicals in the kidney tissue and the relative lack of free radical scavenging, resulting in glomerular filtration membrane, renal tubular ultrastructure changes and dysfunction and renal mitochondrial membrane structure and function impairment , Energy metabolism disorders, increased protein filtration rate, and tubular reabsorption decreased, so that rats after exhaustive exercise urinary protein excretion rate increased.