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为了解四川省自贡地区3～5岁幼儿乙型肝炎病毒(HBV)感染情况,并探索与感染有关的因素,1985年调查了1167名幼儿,其HBV总感染率为41.13％,HBsAg阳性率12.68％。幼儿的HBV感染与母亲HBsAg阳性密切相关。共检查母亲409例,38例HBsAg阳性,其幼儿HBsAg阳性率为50％(19/38),HBsAg阴性的母亲371例,其幼儿HBsAg阳性率9.97％(37/371),来自HBsAg阳性母亲的阳性子女占33.3％(19/56)。1986年随访HBV易感幼儿448例,HBV年感染率为12.95％(58/448),HBsAg年阳转率3.79％。HBV年感染率与原幼儿班级HBsAg阳性率的高低有关。
In order to understand the status of hepatitis B virus (HBV) infection in children aged 3 ~ 5 in Zigong, Sichuan Province and explore the factors related to infection, 1167 infants were investigated in 1985 with a total HBV infection rate of 41.13% and a HBsAg positive rate of 12.68 %. HBV infection in young children is closely related to the positive HBsAg of mothers. A total of 409 mothers and 38 HBsAg-positive mothers were enrolled in this study. The positive rate of HBsAg in their children was 50% (19/38) and 371 HBsAg-negative mothers. The positive rate of HBsAg was 9.97% (37/371) in HBsAg positive mothers Positive children accounted for 33.3% (19/56). In 1986, 448 HBV-susceptible children were followed up, the annual infection rate of HBV was 12.95% (58/448), and the positive rate of HBsAg was 3.79%. The annual infection rate of HBV is related to the level of HBsAg positive rate of the original infant classes.