论文部分内容阅读
直到1961年,胸腺的功能仍然是个迷.一些早期的法国研究者曾推测胸腺可能与免疫应答的发生有关.然而,尽管他们的结论是正确的,但此结论所基于的论据并未被广泛接受.也许大家还记得,那时候淋巴细胞的功能尚未确定.人们普遍认为淋巴细胞是一种短寿命的细胞,仅产生于淋巴结中,并具有各种不同的化生潜力,一个很少有人怀疑的例子是认为淋巴细胞可以转化为红细胞.此后,Gowans证明淋巴细胞是可以再循环的,并可能具有相对较长的寿命;Mitchson证明,就特定的免疫应答而言,必须要有效应细胞;而Miller对胸腺功能的研究则从根本上改变了胸腺研究的现状.由Good领导的一些美国临床研究者认
The function of the thymus remained a mystery until 1961. Some early French researchers had speculated that the thymus might be involved in the development of the immune response.However, although their conclusions were correct, the argument on which the conclusion was based was not widely accepted As you may recall, the function of lymphocytes at that time has not yet been established, and it is generally accepted that lymphocytes are short-lived cells that originate only in the lymph nodes and have a variety of potential for metaplasia, a rare suspicion An example is the belief that lymphocytes can be converted to erythrocytes. Since then, Gowans have demonstrated that lymphocytes are recyclable and may have a relatively long lifespan; Mitchson has demonstrated that effector cells are necessary for a particular immune response; and Miller Studies of thymic function have fundamentally changed the status of thymus research. Some American clinical researchers led by Good recognize